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Fig. 5 | Clinical Epigenetics

Fig. 5

From: The fusiform gyrus exhibits an epigenetic signature for Alzheimer’s disease

Fig. 5

Cross-validation of key AD genes in independent methylation datasets. a Heatmaps show expression fold-changes and methylation fold-changes in PSEN2/WT. The methylation data are from GSE79144 (n = 44). FC, fold-change. b, c PANTHER pathway (b) and GO term (c) enrichment analyses for genes identified from PSEN2/WT neurons and validated in the GSE79144 dataset. d Venn diagrams show the overlap of genes identified from PSEN2/WT, PSEN1/WT, and APOE4/WT neurons and validated in the GSE79144 dataset with a similar methylation change trend

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