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Table 3 Correlations between the model and PFT at baseline

From: A new nucleosomic-based model to identify and diagnose SSc-ILD

  1. The level of the combined model with IGFBP-1, MMP-9, and H3.1 containing cf-nucleosomes (probability of SSC-ILD) computed at T1 was evaluated in relation to PFT for all patients. Significant negative correlations are observed between the model and FVC (% pred) and TLC (% pred). The negative correlation is still significant and even stronger between the model computed with T1 measurements and TLC (% pred) quantified at T2 (but not with FVC at T2), which means that the model could be a predictor of disease progression for TLC (% pred) at T2