| |
Men
|
Women
|
|---|
|
OCDa (n = 32)
|
HCa (n = 56)
| |
OCDa (n = 13)
|
HCa (n = 52)
| |
|---|
|
F
|
pb
|
ηp2c
|
F
|
pb
|
ηp2c
|
|---|
| | |
Statistics: Wilks λ = 0.840, F(4, 81) = 3.843, p = 0.007
|
Statistics: Wilks λ = 0.666, F(4, 58) = 7.285, p < 0.001
|
|---|
|
OXTR1 (exon2)
|
CpG1 (-959)
|
41.49 ± 5.66
|
45.67 ± 4.88
|
7.642
|
0.007
|
0.083†
|
42.75 ± 5.96
|
47.70 ± 3.89
|
10.389
|
< 0.001
|
0.193‡
|
| |
CpG2 (-934)
|
46.41 ± 4.73
|
50.44 ± 4.52
|
14.633
|
< 0.001
|
0.148‡
|
48.87 ± 3.72
|
52.54 ± 3.14
|
5.908
|
0.002
|
0.147‡
|
| |
CpG3 (-924)
|
57.41 ± 4.45
|
59.62 ± 3.82
|
6.044
|
0.016
|
0.067
|
61.49 ± 6.12
|
60.74 ± 3.75
|
0.695
|
0.368
|
0.013
|
|
OXTR2 (exon3)
|
Mean value of CpG1-8
|
14.32 ± 6.31
|
13.34 ± 5.66
|
0.388
|
0.535
|
0.005
|
13.79 ± 4.27
|
14.14 ± 4.57
|
0.274
|
0.599
|
0.005
|
- MANCOVA demonstrated significant between-group difference after controlling for age and education
- MANCOVA multivariate analysis of covariance, OCD obsessive-compulsive disorder, HC healthy control
- aMean ± standard deviation of raw data
- bStatistical significance was set at p < 0.0125 after Bonferroni correction for 4 CpG sites
- cEffect size was calculated using partial eta squared and interpreted according to the rule of Miles and Shevlin (2001)
- †Medium effect (> 0.06)
- ‡Large effect (> 0.14)
