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Fig. 7 | Clinical Epigenetics

Fig. 7

From: G9a regulates tumorigenicity and stemness through genome-wide DNA methylation reprogramming in non-small cell lung cancer

Fig. 7

FOXP1 overexpression resulted in decrease in in vitro cell proliferation and sphere forming capacity of TICs as well as downregulation of H3K9Me2 and stem cells markers. a FOXP1 overexpression in TICs (LCSC2, LCSC4, and LCSC5) resulted in decreased sphere forming capacity (× 10 magnification), b decrease in cell proliferation capacity, and c downregulation of H3k9Me2 and stem cells markers CD44, CD133, and ALDH1A3. (For t test: *P < 0.05, **P < 0.01, and ***P < 0.001)

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Clinical Epigenetics

ISSN: 1868-7083

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