Association between variation of circulating 25-OH vitamin D and methylation of secreted frizzled-related protein 2 in colorectal cancer

Table 1 Clinical, anthropometric, and biochemical variables of CRC patients, according to their 30th percentile of vitamin D

Variables	< 30th percentile of 25-OH vitamin D	> 30th percentile of 25-OH vitamin D	p value
N	20	47	0.347
Age (years)	68.5 ± 9.42	66.06 ± 9.97	0.351
Male/female (%)	12/8, 60/40	34/13, 72/28	0.319
BMI (kg/m²)	27.14 ± 4.12	27.46 ± 4.39	0.779
Waist circumference (cm)	96.20 ± 14.28	99.12 ± 13.73	0.612
Glucose (mg/dl)	126.21 ± 53.89	121.08 ± 40.39	0.711
Insulin (μUI/ml)	5.52 ± 3.68	6.41 ± 5.99	0.481
HOMA-IR	1.58 ± 1.28	2.19 ± 2.37	0.219
Triglycerides (mg/dl)	206.31 ± 112.00	152.98 ± 63.78	0.063
Total cholesterol (mg/dl)	161.89 ± 28.57	174.95 ± 48.30	0.180
HDL-c (mg/dl)	35.58 ± 19.24	42.11 ± 11.98	0.182
LDL-c (mg/dl)	97.74 ± 23.47	105.08 ± 40.06	0.359
Corrected calcium (mg/dl)	9.06 ± 0.49	8.95 ± 0.43	0.410
Alkaline phosphatase(U/l)	74.26 ± 29.01	64.79 ± 29.26	0.239

Data are expressed as mean ± standard deviations or percentage. Asterisk indicates significant difference between the < 30th and > 30th percentile of vitamin D according to Welch’s two sample test. Chi squared test was used for variables expressed as percentage (p < 0.05)
CRC colorectal cancer, BMI body mass index, HOMA-IR homeostasis model assessment of insulin resistance, HDL-c high density lipoprotein cholesterol, LDL-c low density lipoprotein cholesterol

ISSN: 1868-7083