Skip to main content
Fig. 3 | Clinical Epigenetics

Fig. 3

From: Association between variation of circulating 25-OH vitamin D and methylation of secreted frizzled-related protein 2 in colorectal cancer

Fig. 3

Tumor methylation analysis: correlation between SFRP2 promoter methylation status and promoter methylation of genes related to colorectal carcinogenesis in tumor tissue from CRC patients, according to 30th percentile of vitamin D. Correlation between SFRP2 promoter methylation analyses in PBMCs (N = 52), tumor area (N = 60), tumor-free area (N = 55), and VAT (N = 50) from CRC patients and promoter methylation of TIAM1, ZNF397OS, and ZNF543 in tumor area, according to the a < 30th percentile and b > 30th percentile. Pearson’s correlation was performed to determine correlation between methylation analyses. Data are expressed as correlation coefficient. Colored squares indicate significant difference between methylated genes according to the Pearson’s analysis (p < 0.05). Abbreviations: CRC, Colorectal cancer; SFRP2, Secreted frizzled-related protein type 2; PBMCs, peripheral blood mononuclear cells; VAT, Visceral adipose tissue; TIAM1, T cell lymphoma invasion and metastasis 1; ZNF397OS, Zinc Finger Protein 397; ZNF543, Zinc Finger Protein 543

Back to article page

Clinical Epigenetics

ISSN: 1868-7083

Contact us