DNA methylation age calculators reveal association with diabetic neuropathy in type 1 diabetes

Clinical Epigenetics

Table 2 Correlation and mean difference between epigenetic ages and chronological age in EPIC data

	Chronological Age	Pan Tissue	Skin & Blood	PhenoAge	GrimAge
Chronological Age	-	0.76	0.89	0.73	0.76
Pan Tissue	2.0 (4.3)	-	0.75	0.73	0.57
Skin & Blood	-4.2 (3.1)	-6.2 (4.8)	-	0.72	0.72
PhenoAge	-7.7 (5.4)	-9.7 (5.4)	-3.5 (5.5)	-	0.64
GrimAge	5.9 (4.7)	3.9 (6.2)	10.1 (5.3)	13.6 (6.2)	-

The values above the diagonal are Spearman correlation coefficients. The values below the diagonal are mean differences (mean of the age in the row − mean of the age in the column) and their corresponding SDs in brackets. All p values regarding the correlations and the mean differences are < 0.0001

ISSN: 1868-7083