Table 1 Clinical characteristics and viral reservoir markers of the four patient cohorts

# patients

15

17

32

8

 Age (years)

45 (43–54.5)

49 (38–51)

48 (45–53.25)

37 (27–44.75)

 Total cART (years)

11.65 (10.39–11.97)

0 (0–0)

9.80 (6.09–14.73)

0 (0–0)

 Total VL suppression (years)

11.18 (9.82–11.37)

9.72 (0–14.67)

6.53 (5–10.42)

0 (0–0)

 log VL zenith (copies/ml)

5.74 (5.31–5.88)

2.24 (1.79–2.76)

4.93 (4.24–5.52)

6.15 (5.14–6.31)

 CD4 nadir (cells/μl)

413.5 (274.5–539.75)

624 (562–693)

154.5 (51.25–266.25)

483.5 (393.75–520.25)

 CD4 at collection (cells/μl)

961 (737–1129.5)

793 (685–1010)

624.5 (484–885.5)

534 (393.75–617.50)

 CD4/CD8

1.12 (0.8–1.47)

0.91 (0.82–1.47)

0.74 (0.6–0.93)

0.62 (0.37–0.87)

 Total HIV-1 DNA^* (c/M PBMC) [40]

88.14 (46.19–124.02)

48.01 (20.16–56.50)

137.01 (56.08–219.20)

1290.48 (519.63–4428.60)

 Integrated HIV-1 DNA^* (c/M PBMC) [41, 42]

158.00 (122.70–388.55)

28.16 (0–158.41)

586.65 (315.12–918.15)

1802.68 (272.19–3966.55)

 CA HIV-1 usRNA (c/M PBMC) [43]

0.79 (0.28–3.12)

0.44 (0.27–3.51)

6.12 (1.80–10.08)

15.47 (0.62–77.60)

 2-LTR circles (c/M PBMC) [40]

1.48 (0–3.03)

0.77 (0.65–2.70)

1.32 (0.57–2.18)

15.35 (4.82–24.12)