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Table 7 Sensitivity, Specificity, PPV, and NPV at optimal cutoffs with AUC regarding tumor size (0–1 cm)

From: Ultrasensitive DNA hypermethylation detection using plasma for early detection of NSCLC: a study in Chinese patients with very small nodules

GeneSensitivitySpecificityPPVNPVAUC95% CI
CDO182%46%66%67%0.640.49–0.80
TAC161%78%78%61%0.680.56–0.81
SOX1761%77%77%61%0.680.56–0.80
HOXA782%59%72%72%0.730.60–0.87
CDO1, TAC1, SOX1771%82%83%69%0.810.69–0.93
CDO1, SOX17, HOXA764%82%82%64%0.750.62–0.89
  1. Cancer, n = 28; control, n = 22