Table 5 Sensitivity, specificity, PPV, and NPV at optimal cutoffs with AUC regarding tumor size (2.1–3 cm)
Gene | Sensitivity | Specificity | PPV | NPV | AUC | 95% CI |
|---|---|---|---|---|---|---|
CDO1 | 67% | 89% | 94% | 53% | 0.77 | 0.64–0.90 |
TAC1 | 65% | 72% | 85% | 46% | 0.67 | 0.51–0.83 |
SOX17 | 67% | 90% | 94% | 53% | 0.79 | 0.68–0.90 |
HOXA7 | 70% | 83% | 91% | 54% | 0.77 | 0.65–0.89 |
CDO1, TAC1, SOX17 | 88% | 89% | 95% | 76% | 0.91 | 0.83–0.99 |
CDO1, SOX17, HOXA7 | 91% | 90% | 96% | 81% | 0.95 | 0.90–1.00 |