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Table 5 Sensitivity, specificity, PPV, and NPV at optimal cutoffs with AUC regarding tumor size (2.1–3 cm)

From: Ultrasensitive DNA hypermethylation detection using plasma for early detection of NSCLC: a study in Chinese patients with very small nodules

GeneSensitivitySpecificityPPVNPVAUC95% CI
CDO167%89%94%53%0.770.64–0.90
TAC165%72%85%46%0.670.51–0.83
SOX1767%90%94%53%0.790.68–0.90
HOXA770%83%91%54%0.770.65–0.89
CDO1, TAC1, SOX1788%89%95%76%0.910.83–0.99
CDO1, SOX17, HOXA791%90%96%81%0.950.90–1.00
  1. Cancer, n = 43; control, n = 18