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Table 1 Demographics and clinical characteristics of MRS, Army STARRS, and PRISMO

From: Longitudinal epigenome-wide association studies of three male military cohorts reveal multiple CpG sites associated with post-traumatic stress disorder

 

Cases

Controls

p value

Overall

Number

 MRS

63

63

–

126

 Army STARRS

31

47

–

78

 PRISMO

29

33

–

62

Age, mean (SD)

 MRS

22.15 (2.3)

22.36 (3.7)

.71

22.26 (3)

 Army STARRS

23.5 (4.0)

24.6 (4.8)

.26

24.2 (4.4)

 PRISMO

27.1 (9.9)

27.1 (8.7)

1.0

27.1 (9.0)

PTSD pre-deployment, mean (SD)

 MRS, CAPS

10.8 (7.5)

6.8 (6.5)

.002

8.8 (7)

 Army STARRS, PCL-6

7.4 (2.6)

6.8 (2.0)

.40

7.0 (2.2)

 PRISMO, SRIP

28.2 (4.0)

26.4 (4.0)

.10

27.2 (3.9)

PTSD post-deployment, mean (SD)

 MRS, CAPS

58.17 (13.5)

13.36 (6.1)

< .001

35.76 (9.8)

 Army STARRS, PDL-C

52.7 (7.8)

25.8 (8.6)

< .001

36.5 (8.1)

 PRISMO, SRIP

46.1 (8.7)

27.4 (5.1)

< .001

36.1 (6.5)

Combat exposure, mean (SD)

 MRS, DDRI

1.08 (0.8)

0.66 (0.4)

< .001

0.87 (0.6)

 Army STARRS, PCL

9.4 (1.3)

7.9 (2.0)

< .001

8.5 (1.7)

 PRISMO, DEC

8.5 (3.0)

7.2 (2.3)

.07

7.8 (2.5)

Ancestry, N (%)

 MRS

  European

34 (53)

37 (59)

–

71 (56)

  African

5 (8)

5 (8)

–

10 (8)

  Other

24 (39)

21 (33)

–

45 (36)

 Army STARRS

  European

31 (100)

47 (100)

–

78 (100)

 PRISMO

  European

29 (100)

33 (100)

–

62 (100)

  1. CAPS Clinician-Administered PTSD Scale, PCL-6 PTSD Checklist—screener, SRIP Self-Report Inventory for PTSD, PCL-C PTSD Checklist—civilian version, DDRI Deployment Risk and Resilience Inventory, DEC deployment experiences checklist, SD standard deviation. Each study used different scales for PTSD and combat exposure scores; the corresponding scales are included in the row names