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Table 1 ARIES sample characteristics

From: Epigenome-wide association study of seizures in childhood and adolescence

Characteristic

Birth

Childhood

Adolescence

Adolescence (lifetime exposure)

 

With seizures

Without seizures

Total

With seizures

Without seizures

Total

With seizures

Without seizures

Total

With seizures (ever)

Without seizures (ever)

Total

N

25

797

822

7

841

848

12

801

813

58

759

817

Sex (%F)

44%

51%

51%

ND

50%

51%

ND

51%

52%

52%

51%

51%

Age at methylation in years (SD)

NA

7.69 (0.36)

7.44 (0.13)

7.45 (0.14)

17.65 (0.86)

17.11 (1.04)

17.12 (1.04)

17.16 (1.01)

17.10 (1.05)

17.10 (1.04)

Age at seizure assessment in years (SD)

1.54 (0.12)

1.52 (0.06)

1.52 (0.07)

8.60 (0.03)

8.66 (0.16)

8.66 (0.16)

11.70 (0.08)

11.71 (0.12)

11.71 (0.12)

13.12 (0.09)

13.15 (0.17)

13.43 (1.05)

Birthweight in g (SD)

3498.80 (545.54)

3495.08 (478.18)

3495.20 (480.00)

NA

NA

NA

Gestational age in weeks (SD)

39.80 (1.50)

39.55 (1.48)

39.56 (1.48)

Maternal smoking (%Y)

ND

13%

14%

ND

12%

13%

ND

13%

13%

14%

13%

13%

Maternal education (%Uni)

32%

20%

21%

ND

21%

21%

ND

22%

22%

28%

22%

22%

  1. ND not disclosed due to cohort restrictions, NA not applicable