From: Epigenome-wide association study of seizures in childhood and adolescence
Characteristic | Birth | Childhood | Adolescence | Adolescence (lifetime exposure) | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
With seizures | Without seizures | Total | With seizures | Without seizures | Total | With seizures | Without seizures | Total | With seizures (ever) | Without seizures (ever) | Total | |
N | 25 | 797 | 822 | 7 | 841 | 848 | 12 | 801 | 813 | 58 | 759 | 817 |
Sex (%F) | 44% | 51% | 51% | ND | 50% | 51% | ND | 51% | 52% | 52% | 51% | 51% |
Age at methylation in years (SD) | NA | 7.69 (0.36) | 7.44 (0.13) | 7.45 (0.14) | 17.65 (0.86) | 17.11 (1.04) | 17.12 (1.04) | 17.16 (1.01) | 17.10 (1.05) | 17.10 (1.04) | ||
Age at seizure assessment in years (SD) | 1.54 (0.12) | 1.52 (0.06) | 1.52 (0.07) | 8.60 (0.03) | 8.66 (0.16) | 8.66 (0.16) | 11.70 (0.08) | 11.71 (0.12) | 11.71 (0.12) | 13.12 (0.09) | 13.15 (0.17) | 13.43 (1.05) |
Birthweight in g (SD) | 3498.80 (545.54) | 3495.08 (478.18) | 3495.20 (480.00) | NA | NA | NA | ||||||
Gestational age in weeks (SD) | 39.80 (1.50) | 39.55 (1.48) | 39.56 (1.48) | |||||||||
Maternal smoking (%Y) | ND | 13% | 14% | ND | 12% | 13% | ND | 13% | 13% | 14% | 13% | 13% |
Maternal education (%Uni) | 32% | 20% | 21% | ND | 21% | 21% | ND | 22% | 22% | 28% | 22% | 22% |