Table 1 Demographic and clinical characteristics of gingivo-buccal oral squamous cell carcinoma patients included in this study
Clinical characteristics | Methylation discovery set | Methylation validation set | Expression discovery set | Expression validation set |
|---|---|---|---|---|
(n = 43) | (n = 44) | (n = 36) | (n = 36) | |
Age (in years) | ||||
 Range | 26–74 | 26–65 | 26–70 | 32–72 |
 Mean | 50.81 ± 12.77 | 48.7 ± 9.9 | 50.33 ± 11.19 | 49.08 ± 10.43 |
 < 40 | 9 | 7 | 7 | 5 |
 40–45 | 7 | 11 | 6 | 12 |
 46–50 | 6 | 8 | 4 | 6 |
 51–55 | 3 | 7 | 7 | 4 |
 56–60 | 5 | 5 | 5 | 1 |
 > 60 | 13 | 6 | 7 | 8 |
Gender | ||||
 Male | 39 | 36 | 31 | 28 |
 Female | 4 | 8 | 5 | 8 |
Risk-habit | ||||
 Tobacco chewing | 16 | 22 | 17 | 18 |
 Tobacco chewing and (smoking and/or alcohol) | 25 | 17 | 15 | 13 |
 Smoking and/or alcohol | 1 | 4 | 3 | 4 |
 None | 1 | 1 | 1 | 1 |
Tumour stage* | ||||
 T1 | 0 | 10 | 10 | 8 |
 T2 | 12 | 13 | 11 | 10 |
 T3 | 4 | 0 | 1 | 1 |
 T4 | 27 | 21 | 14 | 17 |
Lymph node invasion* | ||||
 N0 | 18 | 22 | 17 | 14 |
 N+ | 25 | 22 | 19 | 22 |