Table 1 Definitions of epigenetics ranging from classical to the translational
From: The timeline of epigenetic drug discovery: from reality to dreams
Classical | Alterations in biological phenotype without an underlying change in genotype |
Biological | Regulation of eukaryotic gene expression through chromatin remodelling |
Chemical | Reversible structural modifications of DNA and histone proteins |
Drug discovery | Targeting proteins that introduce, recognise, or remove DNA and histone modifications |