Fig. 1
From: Epigenetic therapy of novel tumour suppressor ZAR1 and its cancer biomarker function
Inactivation of ZAR1 is associated with decreased survival of lung and kidney cancer patients. a ZAR1 is methylated in lung adenocarcinoma and renal clear cell carcinoma patients across the CGI (TCGA; 450k methylation array infinium chip; beta value; green, CGI; *, significance; red, tumour; blue, normal samples). b ZAR1 expression-dependent survival in lung adenocarcinoma and renal clear cell carcinoma patients (5 years; red, high ZAR1 expression; black, low ZAR1 expression). c ZAR1 methylation-dependent survival of lung adenocarcinoma and renal clear cell carcinoma patients (red, high ZAR1 methylation; blue, low ZAR1 methylation). Right graph shows methylation levels (beta value) split by mean as red vertical line