Table 1 Patient characteristics and demographics of plasma cohorts
Test cohort | Validation cohort | |||
|---|---|---|---|---|
CRC | Controls | CRC | Controls | |
Total (n) | 113 | 87 | 143 | 91 |
Sex n (%) | ||||
Female | 56 (49.6) | 39 (44.8) | 62 (43.0) | 46 (50.5) |
Male | 57 (50.4) | 48 (55.2) | 81 (57.0) | 45 (49.5) |
Age (years) | ||||
mean (SD) | 70.8 (9.1) | 67.2 (6.6) | 73.2 (8.9) | 66.6 (5.6) |
UICC stage, n (%) | ||||
Stage I | 16 (14) | - | 25 (18) | - |
Stage II | 68 (60) | - | 75 (52) | - |
Stage III | 22 (20) | - | 33 (23) | - |
Stage IV | 7 (6) | - | 10 (7) | - |
Tumour diameter (mm) | ||||
Mean (SD) | 53.3 (26.5) | - | 53.3 (32.1) | - |
Histological type n (%) | ||||
Adenocarcinoma | 106 (93.8) | - | 134 (93.7) | - |
Mucinous adenocarcinoma | 4 (3.5) | - | 7 (4.9) | - |
Signet ring cell adenocarcinoma | 1 (0.9) | - | 2 (1.4) | - |
Unspecified or missing | 2 (1.8) | - | 0 (0) | - |
Localization n (%) | ||||
Right (cecum, ascending, transverse) | 48 (42.5) | - | 79 (55.2) | - |
Left (descending, sigmoid) | 47 (41.6) | - | 54 (37.8) | - |
Rectum | 18 (15.9) | - | 10 (7.0) | - |