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Table 1 Patient characteristics and demographics of plasma cohorts

From: Novel DNA methylation biomarkers show high sensitivity and specificity for blood-based detection of colorectal cancer—a clinical biomarker discovery and validation study

 Test cohortValidation cohort
CRCControlsCRCControls
Total (n)1138714391
Sex n (%)
 Female56 (49.6)39 (44.8)62 (43.0)46 (50.5)
 Male57 (50.4)48 (55.2)81 (57.0)45 (49.5)
Age (years)
 mean (SD)70.8 (9.1)67.2 (6.6)73.2 (8.9)66.6 (5.6)
UICC stage, n (%)
 Stage I16 (14)-25 (18)-
 Stage II68 (60)-75 (52)-
 Stage III22 (20)-33 (23)-
 Stage IV7 (6)-10 (7)-
Tumour diameter (mm)
 Mean (SD)53.3 (26.5)-53.3 (32.1)-
Histological type n (%)
 Adenocarcinoma106 (93.8)-134 (93.7)-
 Mucinous adenocarcinoma4 (3.5)-7 (4.9)-
 Signet ring cell adenocarcinoma1 (0.9)-2 (1.4)-
 Unspecified or missing2 (1.8)-0 (0)-
Localization n (%)
 Right (cecum, ascending, transverse)48 (42.5)-79 (55.2)-
 Left (descending, sigmoid)47 (41.6)-54 (37.8)-
 Rectum18 (15.9)-10 (7.0)-
  1. CRC colorectal cancer, UICC Union of International Cancer Control, SD standard deviation