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Table 1 Patient cohort characteristics

From: Region-specific glucocorticoid receptor promoter methylation has both positive and negative prognostic value in patients with estrogen receptor-positive breast cancer

Characteristic All ER+ MA.12 patients GR methylation study cohort
(N = 454) (N = 208)
N % N %
Age
 ≤ 45 years 268 59.0 125 60.1
 > 45 years 186 41.0 83 39.9
Stage (pathological)
 I 40 8.8 12 5.8
 II 387 85.2 180 86.5
 III 27 5.9 16 7.7
Tumor stage (T-stage)
 T1 212 46.7 90 43.3
 T2 213 46.9 102 49.0
 T3/T4 29 6.4 16 7.7
Nodal status
 Node negative 87 19.2 28 13.5
 1–3 nodes 276 60.8 130 62.5
 4–9 nodes 78 17.2 42 20.2
 10+ nodes 13 2.9 8 3.8
Adjuvant chemotherapy
 CEF 104 22.9 52 25.0
 CMF 197 43.4 89 42.8
 AC 153 33.7 67 32.2
Treatment
 Placebo 231 50.9 112 53.8
 Tamoxifen 223 49.1 96 46.2
Outcome
 Deaths 107 23.6 56 26.9
 Recurrences 154 33.9 86 41.3