Skip to main content

Table 1 Patient cohort characteristics

From: Region-specific glucocorticoid receptor promoter methylation has both positive and negative prognostic value in patients with estrogen receptor-positive breast cancer

Characteristic

All ER+ MA.12 patients

GR methylation study cohort

(N = 454)

(N = 208)

N

%

N

%

Age

 ≤ 45 years

268

59.0

125

60.1

 > 45 years

186

41.0

83

39.9

Stage (pathological)

 I

40

8.8

12

5.8

 II

387

85.2

180

86.5

 III

27

5.9

16

7.7

Tumor stage (T-stage)

 T1

212

46.7

90

43.3

 T2

213

46.9

102

49.0

 T3/T4

29

6.4

16

7.7

Nodal status

 Node negative

87

19.2

28

13.5

 1–3 nodes

276

60.8

130

62.5

 4–9 nodes

78

17.2

42

20.2

 10+ nodes

13

2.9

8

3.8

Adjuvant chemotherapy

 CEF

104

22.9

52

25.0

 CMF

197

43.4

89

42.8

 AC

153

33.7

67

32.2

Treatment

 Placebo

231

50.9

112

53.8

 Tamoxifen

223

49.1

96

46.2

Outcome

 Deaths

107

23.6

56

26.9

 Recurrences

154

33.9

86

41.3

Back to article page

Clinical Epigenetics

ISSN: 1868-7083

Contact us