Fig. 3

DNMT3a immunoreactivity in the hippocampal DG. a Representative pictures of DNMT3a staining in the hippocampal DG of TLE patients and controls. Scale bars represent 100 μm. b ImageJ quantification of the integrated density of DNMT3a staining. c Stereological quantification of the area expressing DNMT3a. Error bars show SEM in b and CE in c. **p < 0.01 for significant difference to CTRL. ^†p < 0.05 and ^††p < 0.01 for significant difference to HS⁻ group. ^¥ p < 0.05 for significant difference to HS⁺ group. CTRL = control; HS⁻ = TLE without HS; HS⁺ = TLE with HS; HS⁺FS⁺ = TLE with HS and FS.