Fig. 1

DNMT1 protein expression in the TLE hippocampus (a, b) and neocortex (c, d). a, c Representative Western blot showing DNMT1 (green) in the TLE hippocampus (a) and neocortex (c) compared to controls. GAPDH (red) was used as a protein loading control. b, d Graph showing semi-quantification of the Western blots for hippocampus (b) and neocortex (d). DNMT1 expression was normalized to GAPDH expression. Error bars show SEM. ***p < 0.001 for significant difference to CTRL. ^††p < 0.01 and ^†††p < 0.001 for significant difference to HS⁻ group. MM = molecular weight marker; CTRL = control; HS⁻ = TLE without HS; HS⁺ = TLE with HS; HS⁺FS⁺ = TLE with HS and FS