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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Promoter methylation of SEPT9 as a potential biomarker for early detection of cervical cancer and its overexpression predicts radioresistance

Fig. 1

SEPT9 methylation assay detects cervical cancer with high sensitivity and specificity. a Methylation of SEPT9 in normal tissues, CIN1, CIN 2, CIN 3, and cervical cancer tissues. b, c Receiver operating characteristic (ROC) curve analysis of normal with cancer tissues and normal+ CIN 1 with cancer+ CIN 2+CIN 3 tissues. The area under the ROC curve (AUC) was calculated for the diagnosis of cervical cancer tumors. d Comparison in the two sets on the bases of sensitivity, specificity, AUC, cut-off, and P value

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