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Fig. 4 | Clinical Epigenetics

Fig. 4

From: Suv39h1 promotes facet joint chondrocyte proliferation by targeting miR-15a/Bcl2 in idiopathic scoliosis patients

Fig. 4

Changes of miRNAs targeting Bcl2 in the facet joint chondrocytes of IS patients. ad The expression levels of miRNAs in the facet joint chondrocytes of IS patients and control group. CT, n = 7; IS patients, n = 11. e The mRNA level of miR-15a/16 host gene in the facet joint chondrocytes of IS patients and control group. CT, n = 7; IS patients, n = 11. f The levels of H3K9me3 in the promoter region of miR-15a/16 host gene in the facet joint chondrocytes of IS patients and control group assessed by ChIP assay. P1–P3, three pairs of primers in the promoter region of miR-15a/16 host gene. n = 3. #p < 0.05

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