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Fig. 3 | Clinical Epigenetics

Fig. 3

From: A combined epigenome- and transcriptome-wide association study of the oral masticatory mucosa assigns CYP1B1 a central role for epithelial health in smokers

Fig. 3

Manhattan and QQ pots for epigenome-wide associations with SPY in the masticatory mucosa. a The QQ plot showed some evidence for inflation of association signals (λ = 1.09). b Manhattan plot showing -log10 transformed p values from the ANCOVA plotted against the genomic location of the probes. The horizontal lines indicate the nominal significance threshold (p < 0.05) and the genome-wide significance threshold (p < 10-7)

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Clinical Epigenetics

ISSN: 1868-7083

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