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Table 3 Average methylation of HIF3A.1 and HIF3A.2 by genotype for each of the 14 tag SNPs considered in this analysis

From: Early-life determinants of hypoxia-inducible factor 3A gene (HIF3A) methylation: a birth cohort study

SNP HIF3A.1 methylation (n = 410) HIF3A.2 methylation (n = 595)
rs62111812 Mean (SD) n p Mean (SD) n p
 G/G 70.02 (4.59) 313 0.22 37.95 (9.96) 438 0.1
 G/A 70.93 (4.74) 89   39.93 (8.74) 144  
 A/A 71.19 (1.71) 8   39.47 (10.37) 13  
rs112087991
 T/T 70.39 (4.47) 359 0.22 39.46 (9.44) 522 < 0.0001
 T/C 69.18 (5.38) 49   31.54 (8.67) 70  
 C/C 69.57 (0.61) 2   27.17 (8.30) 3  
rs8102595
 A/A 69.97 (4.60) 331 0.04 38.63 (9.83) 477 0.7
 A/G 71.37 (4.46) 76   37.79 (9.28) 115  
 G/G 72.07 (2.20) 3   37.56 (9.56) 3  
rs3826795
 C/C 70.65 (4.18) 250 0.07 40.42 (9.14) 364 < 0.0001
 C/T 69.68 (5.23) 142   35.76 (9.45) 196  
 T/T 69.03 (4.16) 18   33.28 (11.52) 35  
rs3810298
 C/C 70.42 (4.27) 337 0.26 40.32 (9.02) 476 < 0.0001
 C/T 69.44 (5.95) 67   31.84 (8.63) 109  
 T/T 69.44 (4.36) 6   22.26 (5.88) 10  
rs140454328
 T/T 70.26 (4.61) 398 0.71 38.49 (9.72) 563 0.87
 T/C 69.75 (4.01) 12   38.08 (9.90) 31  
 C/C 0   33.83 (0) 1  
rs36063219
 C/C 70.23 (4.63) 393 0.78 38.41 (9.76) 576 0.46
 C/T 70.55 (3.80) 17   40.08 (8.39) 19  
 T/T 0   0  
rs3752207
 C/C 70.23 (4.43) 357 0.21 38.31 (9.54) 516 0.29
 C/A 70.66 (4.95) 48   39.06 (11.02) 72  
 A/A 66.83 (10.11) 5   43.75 (7.81) 7  
rs4803929
 C/C 70.13 (4.64) 355 0.04 38.6 (9.78) 510 0.29
 C/T 70.7 (4.01) 53   37.41 (9.25) 83  
 T/T 77.88 (4.77) 2   46.49 (8.69) 2  
rs9304657
 T/T 70.34 (4.00) 181 0.75 38.31 (10.18) 288 0.92
 T/C 70.27 (5.00) 178   38.58 (9.48) 237  
 C/C 69.80 (5.12) 51   38.72 (8.58) 70  
rs76789866
 T/T 70.26 (4.58) 385 0.82 38.83 (9.61) 546 0.01
 T/C 70.04 (4.79) 25   34.29 (9.85) 47  
 C/C 0   37.43 (17.94) 2  
rs75952656
 T/T 70.28 (4.67) 382 0.54 38.32 (9.70) 558 0.15
 T/A 69.73 (3.29) 28   40.71 (9.81) 37  
 A/A 0   0  
rs917946
 A/A 70.25 (4.58) 328 0.96 38.07 (9.51) 477 0.05
 A/G 70.23 (4.72) 79   39.74 (10.47) 111  
 G/G 69.44 (2.17) 3   45.28 (7.40) 7  
rs12459580
 G/G 70.08 (4.19) 119 0.65 38.71 (8.36) 168 0.93
 G/C 70.44 (4.74) 212   38.36 (9.89) 295  
 C/C 69.95 (4.77) 79   38.39 (10.91) 132  
  1. p value is from one-way ANOVA. SD standard deviation