|
SNP
|
HIF3A.1 methylation (n = 410)
|
HIF3A.2 methylation (n = 595)
|
|---|
|
rs62111812
|
Mean (SD)
|
n
|
p
|
Mean (SD)
|
n
|
p
|
|
G/G
|
70.02 (4.59)
|
313
|
0.22
|
37.95 (9.96)
|
438
|
0.1
|
|
G/A
|
70.93 (4.74)
|
89
| |
39.93 (8.74)
|
144
| |
|
A/A
|
71.19 (1.71)
|
8
| |
39.47 (10.37)
|
13
| |
|
rs112087991
|
|
T/T
|
70.39 (4.47)
|
359
|
0.22
|
39.46 (9.44)
|
522
|
< 0.0001
|
|
T/C
|
69.18 (5.38)
|
49
| |
31.54 (8.67)
|
70
| |
|
C/C
|
69.57 (0.61)
|
2
| |
27.17 (8.30)
|
3
| |
|
rs8102595
|
|
A/A
|
69.97 (4.60)
|
331
|
0.04
|
38.63 (9.83)
|
477
|
0.7
|
|
A/G
|
71.37 (4.46)
|
76
| |
37.79 (9.28)
|
115
| |
|
G/G
|
72.07 (2.20)
|
3
| |
37.56 (9.56)
|
3
| |
|
rs3826795
|
|
C/C
|
70.65 (4.18)
|
250
|
0.07
|
40.42 (9.14)
|
364
|
< 0.0001
|
|
C/T
|
69.68 (5.23)
|
142
| |
35.76 (9.45)
|
196
| |
|
T/T
|
69.03 (4.16)
|
18
| |
33.28 (11.52)
|
35
| |
|
rs3810298
|
|
C/C
|
70.42 (4.27)
|
337
|
0.26
|
40.32 (9.02)
|
476
|
< 0.0001
|
|
C/T
|
69.44 (5.95)
|
67
| |
31.84 (8.63)
|
109
| |
|
T/T
|
69.44 (4.36)
|
6
| |
22.26 (5.88)
|
10
| |
|
rs140454328
|
|
T/T
|
70.26 (4.61)
|
398
|
0.71
|
38.49 (9.72)
|
563
|
0.87
|
|
T/C
|
69.75 (4.01)
|
12
| |
38.08 (9.90)
|
31
| |
|
C/C
|
–
|
0
| |
33.83 (0)
|
1
| |
|
rs36063219
|
|
C/C
|
70.23 (4.63)
|
393
|
0.78
|
38.41 (9.76)
|
576
|
0.46
|
|
C/T
|
70.55 (3.80)
|
17
| |
40.08 (8.39)
|
19
| |
|
T/T
|
–
|
0
| |
–
|
0
| |
|
rs3752207
|
|
C/C
|
70.23 (4.43)
|
357
|
0.21
|
38.31 (9.54)
|
516
|
0.29
|
|
C/A
|
70.66 (4.95)
|
48
| |
39.06 (11.02)
|
72
| |
|
A/A
|
66.83 (10.11)
|
5
| |
43.75 (7.81)
|
7
| |
|
rs4803929
|
|
C/C
|
70.13 (4.64)
|
355
|
0.04
|
38.6 (9.78)
|
510
|
0.29
|
|
C/T
|
70.7 (4.01)
|
53
| |
37.41 (9.25)
|
83
| |
|
T/T
|
77.88 (4.77)
|
2
| |
46.49 (8.69)
|
2
| |
|
rs9304657
|
|
T/T
|
70.34 (4.00)
|
181
|
0.75
|
38.31 (10.18)
|
288
|
0.92
|
|
T/C
|
70.27 (5.00)
|
178
| |
38.58 (9.48)
|
237
| |
|
C/C
|
69.80 (5.12)
|
51
| |
38.72 (8.58)
|
70
| |
|
rs76789866
|
|
T/T
|
70.26 (4.58)
|
385
|
0.82
|
38.83 (9.61)
|
546
|
0.01
|
|
T/C
|
70.04 (4.79)
|
25
| |
34.29 (9.85)
|
47
| |
|
C/C
|
–
|
0
| |
37.43 (17.94)
|
2
| |
|
rs75952656
|
|
T/T
|
70.28 (4.67)
|
382
|
0.54
|
38.32 (9.70)
|
558
|
0.15
|
|
T/A
|
69.73 (3.29)
|
28
| |
40.71 (9.81)
|
37
| |
|
A/A
|
–
|
0
| |
–
|
0
| |
|
rs917946
|
|
A/A
|
70.25 (4.58)
|
328
|
0.96
|
38.07 (9.51)
|
477
|
0.05
|
|
A/G
|
70.23 (4.72)
|
79
| |
39.74 (10.47)
|
111
| |
|
G/G
|
69.44 (2.17)
|
3
| |
45.28 (7.40)
|
7
| |
|
rs12459580
|
|
G/G
|
70.08 (4.19)
|
119
|
0.65
|
38.71 (8.36)
|
168
|
0.93
|
|
G/C
|
70.44 (4.74)
|
212
| |
38.36 (9.89)
|
295
| |
|
C/C
|
69.95 (4.77)
|
79
| |
38.39 (10.91)
|
132
| |
- p value is from one-way ANOVA. SD standard deviation
