Skip to main content

Table 2 BS-DMPs (adjusted P value < 0.05) associated with multiple sclerosis (cohort 1)

From: Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis

probeID Chr Pos mean_MS mean_ctr Δβ P value adj. P value Gene namea Featurea
cg25139877 1 247691111 0.90 0.88 0.02 1.02E−06 0.0391 LOC148824 Body
cg19274180 2 2726437 0.62 0.39 0.23 6.79E−08 0.0062
cg03466083 5 139088813 0.51 0.42 0.08 5.85E−07 0.0273
cg00211215 6 32552246 0.32 0.23 0.09 1.14E−08 0.0028 HLA-DRB1 Body
cg01414268 8 2480911 0.26 0.20 0.06 1.10E−06 0.0391
cg10596483 8 143751796 0.35 0.47 − 0.12 7.26E−08 0.0062 JRK TSS1500
cg27224751 15 41096921 0.53 0.79 − 0.26 8.73E−08 0.0062 DNAJC17 Body
cg14789911 21 47582049 0.65 0.43 0.22 1.25E−06 0.0411 C21orf56 Body
cg03311906 22 20376405 0.77 0.57 0.20 5.23E−07 0.0273
cg15242686 22 24348715 0.39 0.50 − 0.11 3.45E−07 0.0211 GSTTP1 TSS1500
cg04234412 22 24373322 0.49 0.32 0.17 1.31E−08 0.0028 LOC391322 Body
cg01238044 22 24384105 0.30 0.17 0.13 6.40E−07 0.0273 GSTT1 Body
cg17005068 22 24384525 0.51 0.34 0.18 3.95E−08 0.0056 GSTT1 TSS1500
  1. aFrom UCSC annotations. Chr Chromosome, Pos position, MS multiple sclerosis, ctr non-neurological controls, Δβ delta β-value, adj. P val adjusted P value, TSS transcription starting site