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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Prenatal adverse environment is associated with epigenetic age deceleration at birth and hypomethylation at the hypoxia-responsive EP300 gene

Fig. 2

Association between epigenetic age acceleration and cerebroplacental ratio measured during the third trimester. Epigenetic age delta (ΔGA) corresponds to estimated epigenetic age minus chronological age. Thus, ΔGA-positive values reflect epigenetic age acceleration while negative values point out the presence of epigenetic age deceleration. The cerebroplacental ratio (CPR) is calculated as the ratio between the MCAPI and UAPI. Both variables were significantly correlated when adjusting for sex, chronological gestational age, birth weight, and gestational age at ultrasound

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