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Table 1 Distribution of ZBTB12 factor loadings (N = 342) and specific CpG unit methylation in the Moli-family cohort

From: ZBTB12 DNA methylation is associated with coagulation- and inflammation-related blood cell parameters: findings from the Moli-family cohort

CpG number Factor loading Methylation levels
Factor 1 Factor 2 N Mean SD
3–4 0.83 0.03 440 0.37 0.09
26 0.80 − 0.04 453 0.37 0.10
1 0.74 0.16 458 0.35 0.10
11 0.70 0.20 415 0.28 0.14
5 0.58 0.19 419 0.11 0.09
27 0.56 0.10 408 0.43 0.14
18–19–20 0.47 0.12 411 0.71 0.12
6 0.43 − 0.15 450 0.64 0.20
9–10 0.27 0.89 457 0.24 0.07
21 0.23 0.83 458 0.09 0.06
16 0.01 0.80 458 0.17 0.10
8 0.26 0.78 457 0.06 0.03
7 0.11 − 0.34 421 0.63 0.14
  1. PCA resulted in the identification of two factors with eigenvalue > 1. Factor loadings of the main sites for each factor are highlighted in italics