Fig. 1

ZBTB12 structure (chr6:31899617-31901992, GRCh38/hg38 Assembly). Exon1 is indicated by a full blue box (“EXON1”). Two CpG islands are located in the gene (“CGI1” and “CGI2,” depicted as light and dark green boxes, respectively). CpG islands are defined based on the formula described by Gardiner–Garden et al. J Mol Biol. 1987;196(2):261–282. ZBTB12 conservation across vertebrates is displayed as blue histograms at the bottom of the figure using the Vertebrate Multiz Alignment & Conservation (100 Species) UCSC track. Sequenom studied region (chr6: 31899847-31900326, GRCh38/hg38 Assembly) is depicted as red box