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Table 4 Multiple linear regression showing the association between mean PM2.5 (μg/m3) from 2006–2011 and AHRR (cg05575921) methylation

From: Methylation at cg05575921 of a smoking-related gene (AHRR) in non-smoking Taiwanese adults residing in areas with different PM2.5 concentrations

Variable

Model 1

Model 2

β

P value

β

P value

PM2.5

− 0.00115

< .001

− 0.00124

< .001

Sex (reference: women)

    

 Men

− 0.01489

< .001

− 0.01416

< .001

Age

− 0.00023

0.083

− 0.00022

0.116

Alcohol Drinking (reference: no)

    

 Former

− 0.01043

0.357

− 0.01494

0.238

 Current

− 0.00534

0.473

− 0.00430

0.603

Exercise (reference: no)

    

 Yes

− 0.00196

0.495

− 0.00183

0.545

BMI

− 0.00007

0.844

0.00003

0.942

SHS (reference: no)

  

–

–

 Yes

− 0.00115

0.802

–

–

  1. Model 1 included SHS in the analysis, model 2 excluded SHS from the analysis, SHS second-hand smoke