Exploring targets of TET2-mediated methylation reprogramming as potential discriminators of prostate cancer progression

Table 3 Univariate and multivariate logistic regression analyses for classification of prostate tumor vs normal prostate

Gene	Univariate p value	Univariate odds ratio	Univariate confidence interval	Multivariate p value	Multivariate odds ratio	Multivariate confidence interval
ASB2	2.05E−08***	0.998	0.997–0.998	0.96	1	0.998–1.002
ETNK2	2.34E−13***	0.99	0.987–0.993	0.1	0.996	0.992–1.001
KCNJ15	1.50E−10***	0.983	0.978–0.988	0.17	0.995	0.988–1.002
MEIS2	7.25E−14***	0.997	0.997–0.998	0.019*	0.998	0.997–1.000
NRG1	2.07E−08***	0.97	0.959–0.980	0.028*	0.98	0.964–0.998
NTN1	2.08E−06***	0.997	0.995–0.998	0.028*	1.004	1.000–1.007
NUDT10	1.26E−05***	0.998	0.997–0.999	0.010*	0.999	0.998–1.000
PDE4A	3.37E−10***	0.993	0.991–0.995	0.064	0.997	0.993–1.000
SRPX	1.42E−07***	0.994	0.992–0.997	0.89	1	0.997–1.003

Statistical significance indicated by asterisks: *0.01 < p < 0.05; **0.001 < p < 0.01; ***p < 0.001
Note: odds ratios are modest due to the large scale range of the data (see Fig. 4b)