CpG names | Alcohol intake | CpG characteristics |
---|
β
(1SD)
1
|
q
val
2
| % change3 | Associated genes | Gene region4 | Island5 | Chr |
---|
1 | cg03199996 | 0.263 | 0.029 | 9.7 | FAM65C | Body | Open sea | 20 |
2 | cg07382687 | − 0.257 | 0.048 | − 10.3 | CREB3L2 | Body | Open sea | 7 |
- 1Coefficients for 1 standard deviation alcohol intake (SD = 11.8)
- 2False discovery rate (FDR) adjusted p values
- 3Percentage of methylation change for an increase of 1 SD increase of alcohol intake
- 4Gene region feature category describing the CpG position, from UCSC. TSS200 200 bases upstream of the transcriptional start site (TSS); TSS1500 1500 bases upstream of the TSS; 5′UTR within the 5′ untranslated region, between the TSS and the ATG start site; body between the ATG and stop codon irrespective of the presence of introns, exons, TSS, or promoters; 3′UTR between the stop codon and poly A signal
- 5The location of the CpG relative to the CpG island. Shore 0–2 kb from island, Shelf 2–4 kb from island, N upstream (5′) of CpG island, S downstream (3′) of CpG island, open sea isolated CpGs in the genome