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Table 5 Differential mean methylation of candidate genes in buccal cell DNA of children after maternal antenatal CBT or TAU

From: Exploring the effect of antenatal depression treatment on children’s epigenetic profiles: findings from a pilot randomized controlled trial

Gene

Δß

95%CI

P

NR3C1

0.004

−0.004 to 0.011

0.32

NR3C1 Promoter

0.002

−0.010 to 0.011

0.65

SLC6A4

0.013

−0.007 to 0.035

0.09

OXTR

0.008

−4.7e-05 to 1.6e-02

0.04

NR3C2

0.002

−0.005 to 0.009

0.6

MEST

0.013

0.003 to 0.024

0.02

MEG3

0.012

0.00004 to 0.023

0.04

IFG2

0.005

−0.014 to 0.028

0.65

HSD11B1

0.004

−0.0123 to 0.019

0.61

HSD11B2

0.003

−0.003 to 0.010

0.29

H19

0.019

0.003 to 0.041

0.03

CRHR1

0.013

−0.0003 to 0.027

0.06

CRHR2

0.019

0.002 to 0.032

0.02

CRHRBP

-0.003

−0.033 to 0.033

0.93

CRH

0.001

−0.014 to 0.015

0.98

BDNF

0.001

−0.005 to 0.008

0.38

FKBP5

0.006

−0.0003 to 0.0139

0.051

  1. Δß = mean ß (TAU) - mean ß (CBT)
  2. CBT cognitive behavioral therapy, TAU treatment as usual