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Table 2 Significantly differentially methylated CpG probes in AMD RPE cells with FDR < 20% also showing a mean methylation difference between AMD and normal RPE cells of 10% minimum (FDR < 0.2, Δβ ≥ 0.1 (10%))

From: Whole-genome methylation profiling of the retinal pigment epithelium of individuals with age-related macular degeneration reveals differential methylation of the SKI, GTF2H4, and TNXB genes

Probe ID Gene Adjusted p value Δβ Chromosome CpG position Accession reference Probe location
cg18486102 FAIM2 1.08E−12 0.20 12 50297777 NM_012306 TSS200
cg18934822 SKI 1.18E−09 0.11 1 2191402 NM_003036 Body
cg23169512   2.08E−08 0.33 15 60290666   Intragenic
cg22508626 GTF2H4 7.03E−07 0.11 6 30879905 NM_001517 Body
cg01560972 RIC3 2.03E−06 0.33 11 8190837 NM_024557 TSS1500
cg04838987 EDEM2 3.98E−06 0.18 20 33734406 NM_001145025 Body
cg11241206 BDNF 4.44E−06 0.30 11 27723128 NM_001143813 TSS1500
cg26347887 EIF2AK3 5.16E−06 0.28 2 88927196 NM_004836 TSS200
  1. TSS transcription start site, 5′UTR 5-untranslated region, 3′-UTR 3-untranslated region, Body gene body, Intragenic intragenic region