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Table 1 Summary of clinical features and demographic information of samples in this study

From: TRIM4 is associated with neural tube defects based on genome-wide DNA methylation analysis

NTDs group Sex Gestational weeks Types of deformity Control group 1 Sex Gestational weeks Causes of odinopoeia Control group 2 Sex Gestational weeks Causes of odinopoeia
S1(ES3) F 29 weeks + 3 days Spina bifida N1 (807416) F 28 weeks + 6 days Inevitable abortion S156 F 28 weeks + 1 day Dead fetus in the uterus
S2(ES6) F 30 weeks Spina bifida N2 (707666) F 30 weeks + 3 days Mild pericardial effusion S104 F 29 weeks Increased cardiothoracic ratio
S5(ES7) M 33 weeks Spina bifida S90 M 34 weeks Unplanned pregnancy N2-5-YANG M 34 weeks Dead fetus in the uterus
ES1 F 26 weeks Meningomyelocele S108 F 25 weeks + 6 days Inevitable abortion S146 F 25 weeks + 3 days Dead fetus in the uterus
ES2 M 35 weeks + 3 days Hydrocephaly S89 M 34 weeks + 5 days Dead fetus in the uterus S92 M 34 weeks + 1 day Unplanned pregnancy
ES4 F 27 weeks + 6 days Spina bifida S189 F 26 weeks + 6 days Inevitable abortion N2-2-SUN F 27 weeks + 1 day Adenoma in the right lung
ES8 F 30 weeks + 6 days Spina bifida, hydrocephaly S86 F 32 weeks + 1 day Unplanned pregnancy S57 F 32 weeks Hydrops.
ES9 M 24 weeks Spina bifida S158 M 24 weeks + 1 day Intrauterine distress S121 M 23 weeks + 2 days Unplanned pregnancy
NJS2 M 26 weeks + 6 days Hydrocephaly S169 M 26 weeks + 4 days Unplanned pregnancy S117 M 26 weeks + 3 days Inevitable abortion
NJS3 F 29 weeks + 6 days Hydrocephaly N3 F 31 weeks + 4 days Biparietal diameter and femur length discrepancy S148 F 29 weeks Hydronephrosis in double kidney
NJS4 M 37 weeks + 2 days Hydrocephaly N5 M 38 weeks + 2 days Pleural effusion N2-8-XIA M 37 weeks + 2 days Hydrops.
NJS5 M 29 weeks + 4 days Hydrocephaly S168 M 29 weeks + 4 days Threatened premature labor N2-10-XU M 30 weeks Inevitable abortion
NJS6 M 31 weeks + 1 day Hydrocephaly N4 M 30 weeks + 1 day Eclampsia S83 M 30 week + 3 days Pleural effusions
NJS8 F 24 weeks + 1 day Spina bifida, hydrocephaly S109 F 25 weeks + 6 days Inevitable abortion N2-4-WANG F 24 weeks Unplanned pregnancy