Table 1 Summary of clinical features and demographic information of samples in this study
From: TRIM4 is associated with neural tube defects based on genome-wide DNA methylation analysis
NTDs group | Sex | Gestational weeks | Types of deformity | Control group 1 | Sex | Gestational weeks | Causes of odinopoeia | Control group 2 | Sex | Gestational weeks | Causes of odinopoeia |
|---|---|---|---|---|---|---|---|---|---|---|---|
S1(ES3) | F | 29Â weeks + 3Â days | Spina bifida | N1 (807416) | F | 28Â weeks + 6Â days | Inevitable abortion | S156 | F | 28Â weeks + 1Â day | Dead fetus in the uterus |
S2(ES6) | F | 30Â weeks | Spina bifida | N2 (707666) | F | 30Â weeks + 3Â days | Mild pericardial effusion | S104 | F | 29Â weeks | Increased cardiothoracic ratio |
S5(ES7) | M | 33Â weeks | Spina bifida | S90 | M | 34Â weeks | Unplanned pregnancy | N2-5-YANG | M | 34Â weeks | Dead fetus in the uterus |
ES1 | F | 26Â weeks | Meningomyelocele | S108 | F | 25Â weeks + 6Â days | Inevitable abortion | S146 | F | 25Â weeks + 3Â days | Dead fetus in the uterus |
ES2 | M | 35Â weeks + 3Â days | Hydrocephaly | S89 | M | 34Â weeks + 5Â days | Dead fetus in the uterus | S92 | M | 34Â weeks + 1Â day | Unplanned pregnancy |
ES4 | F | 27Â weeks + 6Â days | Spina bifida | S189 | F | 26Â weeks + 6Â days | Inevitable abortion | N2-2-SUN | F | 27Â weeks + 1Â day | Adenoma in the right lung |
ES8 | F | 30Â weeks + 6Â days | Spina bifida, hydrocephaly | S86 | F | 32Â weeks + 1Â day | Unplanned pregnancy | S57 | F | 32Â weeks | Hydrops. |
ES9 | M | 24Â weeks | Spina bifida | S158 | M | 24Â weeks + 1Â day | Intrauterine distress | S121 | M | 23Â weeks + 2Â days | Unplanned pregnancy |
NJS2 | M | 26Â weeks + 6Â days | Hydrocephaly | S169 | M | 26Â weeks + 4Â days | Unplanned pregnancy | S117 | M | 26Â weeks + 3Â days | Inevitable abortion |
NJS3 | F | 29Â weeks + 6Â days | Hydrocephaly | N3 | F | 31Â weeks + 4Â days | Biparietal diameter and femur length discrepancy | S148 | F | 29Â weeks | Hydronephrosis in double kidney |
NJS4 | M | 37Â weeks + 2Â days | Hydrocephaly | N5 | M | 38Â weeks + 2Â days | Pleural effusion | N2-8-XIA | M | 37Â weeks + 2Â days | Hydrops. |
NJS5 | M | 29Â weeks + 4Â days | Hydrocephaly | S168 | M | 29Â weeks + 4Â days | Threatened premature labor | N2-10-XU | M | 30Â weeks | Inevitable abortion |
NJS6 | M | 31Â weeks + 1Â day | Hydrocephaly | N4 | M | 30Â weeks + 1Â day | Eclampsia | S83 | M | 30Â week + 3Â days | Pleural effusions |
NJS8 | F | 24Â weeks + 1Â day | Spina bifida, hydrocephaly | S109 | F | 25Â weeks + 6Â days | Inevitable abortion | N2-4-WANG | F | 24Â weeks | Unplanned pregnancy |