Clinical Epigenetics

Table 3 Loss of epigenetic mark immunoreactivity among different cell types in newborn pig temporal/parietal cortices

From: DNA methylation and histone post-translational modification stability in post-mortem brain tissue

		Nuclear morphology
Epigenetic modification	Observed change (time point)	Large round	Intermediate	Small round	Small irregular/longer	Endothelial/smooth muscle
5mC	72 h	Minimal	Minimal	Minimal
5hmC	72 h			Minimal
5fC	72 h
5caC	72 h	n/a
H3K4me3	72 h	Minimal			Minimal	Minimal
H3K9me2, K9me3	72 h	Minimal			Minimal
H3K27me2	72 h	Minimal
H3K27me3	72 h	Minimal			Minimal
H3K36me3	72 h					Minimal
H3K9ac	48 h	Moderate
H3K14ac^A	72 h	n/a	Minimal	Minimal	Minimal
H3K27ac	72 h	Moderate	Minimal	Moderate
H4K5ac	48 h	Moderate	Minimal		Minimal
H4K12ac	48 h	Minimal			Minimal
H4K16ac	48 h	Minimal
Total H3	48 h	Minimal	Minimal	Minimal	Minimal	Minimal
Total H4	72 h				Minimal

^ALarge nuclei were not positively stained at 0 h
A blank cell represents no change

Back to article page

ISSN: 1868-7083

Contact us

General enquiries: journalsubmissions@springernature.com