Fig. 7
From: The degree of mitochondrial DNA methylation in tumor models of glioblastoma and osteosarcoma
Pearson correlation tests between levels of mtDNA methylation and mtDNA transcription during 143B cell tumorigenesis. The level of ND5 gene expression is correlated with the levels of DNA methylation at sites a 527 and b 545 of the HSP region. The level of ND6 gene expression is correlated with the DNA methylation levels at c site 412 of the LSP region. Gene expression values (mean ± SEM; n = 3) were analyzed against the mean values of the methylation levels of each site. R2 and significance are shown in each plot