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Table 5 DMRs related to pubertal process in this study that were previously reported by Almstrup during transition to puberty

From: Methylome profiling of healthy and central precocious puberty girls

DMR Chr DMR start DMR end DMR width Number of CpGs Mean beta difference (pre-pubertal minus post-pubertal values) Minimum FDR Promoters of genes included in the DMR
DMR_10849* 7 100,463,206 100465221 2016 11 − 0.050845841 8.06E−11 TRIP6
DMR_10848* 7 100,449,647 100,450,634 988 8 − 0.011123245 8.92E−22 SLC12A9, RP11-126 L15.4
DMR_4835 17 7,834,607 7,835,519 913 13 − 0.004918456 2.27E−35 TRAPPC1, KCNAB3, CNTROB
DMR_5149 17 4,6687,312 46,692,859 5548 34 − 0.010869697 1.33E−51 HOXB8, HOXB7
DMR_6184 19 46,996,347 46,999,444 3098 15 − 0.017502407 1.01E−10 AC011484.1, PNMAL2
DMR_9947* 6 31,543,289 31,543,686 398 10 − 0.024464641 1.26944E−07 TNF
DMR_5887* 19 15,528,530 15,530,737 2208 18 − 0.007917542 1.19E−30 AKAP8L
DMR_1838* 11 2,925,594 2,927,247 1654 15 0.005243223 2.57836E−07 SLC22A18, SLC22A18AS
DMR_9898* 6 30,290,258 30,296,049 5792 57 − 0.014466232 3.04E−79 TRIM39, HCG18
DMR_2718* 12 52,626,427 52,627,576 1150 10 − 0.024084513 1.47E−20 KRT7
  1. Abbreviations: Chr chromosome, DMR differentially methylated regions, FDR false discovery rate
  2. *DMRs with methylation changes in the same direction