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Table 4 Quantitative analysis of the CD14 and HLA-DOA mRNA expression in tumour and adjacent normal mucosa

From: Two histologically colorectal carcinomas subsets from the serrated pathway show different methylome signatures and diagnostic biomarkers

Gene

Sample type

N

Mean ± SD

Median

IR

CD14

SAC-T

19

0.166 ± 0.16

0.133

0.509

 

hmMSI-H-T

22

0.066 ± 0.16

0.004

0.718

 

p value

   

0.004

 

SAC-N

7

0.191 ± 0.17

0.198

0.386

 

hmMSI-H-N

7

0.129 ± 0.24

0.037

0.667

 

p value

   

0.383

HLA-DOA

SAC-T

19

0.0617 ± 0.11

0.099

0.375

 

hmMSI-H-T

22

0.021 ± 0.03

0.006

0.138

 

p value

   

0.047

 

SAC-N

7

0.135 ± 0.01

0.0098

0.034

 

hmMSI-H-N

7

0.07 ± 0.008

0.037

0.021

 

p value

   

0.620

  1. SAC-T tumoural tissue from serrated adenocarcinoma, hmMSI-H-T tumoural tissue from histological and molecular high-level microsatellite unstable colorectal carcinoma, SAC-N normal tissue adjacent to SAC, hmMSI-H-N normal tissue adjacent to hmMSI-H
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Clinical Epigenetics

ISSN: 1868-7083

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