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Table 4 Quantitative analysis of the CD14 and HLA-DOA mRNA expression in tumour and adjacent normal mucosa

From: Two histologically colorectal carcinomas subsets from the serrated pathway show different methylome signatures and diagnostic biomarkers

Gene Sample type N Mean ± SD Median IR
CD14 SAC-T 19 0.166 ± 0.16 0.133 0.509
  hmMSI-H-T 22 0.066 ± 0.16 0.004 0.718
  p value     0.004
  SAC-N 7 0.191 ± 0.17 0.198 0.386
  hmMSI-H-N 7 0.129 ± 0.24 0.037 0.667
  p value     0.383
HLA-DOA SAC-T 19 0.0617 ± 0.11 0.099 0.375
  hmMSI-H-T 22 0.021 ± 0.03 0.006 0.138
  p value     0.047
  SAC-N 7 0.135 ± 0.01 0.0098 0.034
  hmMSI-H-N 7 0.07 ± 0.008 0.037 0.021
  p value     0.620
  1. SAC-T tumoural tissue from serrated adenocarcinoma, hmMSI-H-T tumoural tissue from histological and molecular high-level microsatellite unstable colorectal carcinoma, SAC-N normal tissue adjacent to SAC, hmMSI-H-N normal tissue adjacent to hmMSI-H