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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Idiopathic male infertility is strongly associated with aberrant DNA methylation of imprinted loci in sperm: a case-control study

Fig. 2

Examination of methylation patterns of the three imprinted genes in the sperm of infertile males and fertile controls by combined bisulfite PCR restriction analysis (COBRA) and bisulfite-sequencing PCR (BSP). A Representative results of the COBRA (a) and BSP (b) analysis of H19. B Representative results of the COBRA (a) and BSP (b) analysis of GNAS. C Representative results of the COBRA (a) and BSP (b) analysis of DIRAS3. Filled and open circles represent methylated and unmethylated CpGs, respectively. M, molecular weight markers; Control, blood DNA (hemimethylated DNA)

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Clinical Epigenetics

ISSN: 1868-7083

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