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Fig. 6 | Clinical Epigenetics

Fig. 6

From: Multiomics analyses identified epigenetic modulation of the S100A gene family in Kawasaki disease and their significant involvement in neutrophil transendothelial migration

Fig. 6

The concept of perfect cases of negatively correlated genes and CpG markers. Among the three sample sets, we were especially interested in the variations of gene and CpG markers from HC to KD1 and from KD1 to KD3. The mUD and gUD individually denoted the CpG markers and genes that were first upregulated from HC to KD1 and then downregulated from KD1 to KD3, indicating the up-then-down cases. mDU and gDU individually denoted the CpG markers and genes that were first downregulated from HC to KD1 and then upregulated from KD1 to KD3, forming the down-then-up cases. In this manner, we identified 83 genes and their promoter CpG markers that were the perfect cases of negatively correlated genes and CpG markers

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Clinical Epigenetics

ISSN: 1868-7083

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