Fig. 4From: Multiomics analyses identified epigenetic modulation of the S100A gene family in Kawasaki disease and their significant involvement in neutrophil transendothelial migrationThe scatter plots of gene expression variations and DNA methylation variations for CpG markers located within the putative promoters. The X axis presented the gene expression variation determined with the HTA2.0 assay. The Y axis presented the DNA methylation variation determined with the M450K assay. Each dot denoted the regulation pair of one significant gene and one significant CpG marker; only those with a p value < 0.05 were concerned significant. For each comparison in each column, the Spearman’s rank correlation coefficient (denoted as rho) was labeled. The correlation coefficient was calculated with the data from the full-length promoter (the Both column), in the − 5000 to − 1 bp region (the Upstream column) and the + 1 to + 3000 bp region (the Downstream column). The sample size for sub-figures a to i were in order: 28,776, 3903, 61,055, 18,068, 2318, 36,770, 10,698, 1575, and 24,285Back to article page