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Table 6 Diagnostic values for TB of selected genes using different models

From: Vitamin D and the promoter methylation of its metabolic pathway genes in association with the risk and prognosis of tuberculosis

Gene Model 1 Model 2 Model 3 Model 4
AUC 95% CI P AUC 95% CI P AUC 95% CI P AUC 95% CI P
CYP24A1 0.707 0.641–0.772 < 0.001 0.794 0.737–0.851 < 0.001 0.794 0.737–0.851 < 0.001 0.793 0.736–0.850 < 0.001
CYP27A1 0.739 0.675–0.802 < 0.001 0.760 0.699–0.821 < 0.001 0.760 0.699–0.821 < 0.001 0.747 0.685–0.809 < 0.001
CYP27B1 0.735 0.671–0.799 < 0.001 0.739 0.675–0.803 < 0.001 0.739 0.675–0.803 < 0.001 0.747 0.684–0.810 < 0.001
CYP2R1 0.578 0.506–0.650 0.037 0.611 0.540–0.683 0.003 0.743 0.679–0.806 < 0.001
VDR 0.664 0.596–0.732 < 0.001 0.709 0.644–0.775 < 0.001 0.740 0.677–0.803 < 0.001 0.758 0.696–0.819 < 0.001
  1. AUC area under the curve, CI confidence interval