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Table 6 Diagnostic values for TB of selected genes using different models

From: Vitamin D and the promoter methylation of its metabolic pathway genes in association with the risk and prognosis of tuberculosis

Gene

Model 1

Model 2

Model 3

Model 4

AUC

95% CI

P

AUC

95% CI

P

AUC

95% CI

P

AUC

95% CI

P

CYP24A1

0.707

0.641–0.772

< 0.001

0.794

0.737–0.851

< 0.001

0.794

0.737–0.851

< 0.001

0.793

0.736–0.850

< 0.001

CYP27A1

0.739

0.675–0.802

< 0.001

0.760

0.699–0.821

< 0.001

0.760

0.699–0.821

< 0.001

0.747

0.685–0.809

< 0.001

CYP27B1

0.735

0.671–0.799

< 0.001

0.739

0.675–0.803

< 0.001

0.739

0.675–0.803

< 0.001

0.747

0.684–0.810

< 0.001

CYP2R1

0.578

0.506–0.650

0.037

0.611

0.540–0.683

0.003

0.743

0.679–0.806

< 0.001

VDR

0.664

0.596–0.732

< 0.001

0.709

0.644–0.775

< 0.001

0.740

0.677–0.803

< 0.001

0.758

0.696–0.819

< 0.001

  1. AUC area under the curve, CI confidence interval