Skip to main content

Table 3 Correlations of DNA methylation levels with FADS1 and FADS2 gene expression

From: FADS1-FADS2 genetic polymorphisms are associated with fatty acid metabolism through changes in DNA methylation and gene expression

Region CpG site FADS1 mRNA levels FADS2 mRNA levels
r P 1 r P 2
Region1 CpG_9 − 0.501 < 0.001 − 0.363 0.020
CpG_10 − 0.527 < 0.001 − 0.420 0.006
CpG_11 − 0.428 0.005 − 0.419 0.006
CpG_12 − 0.157 0.328 − 0.085 0.600
Region2 CpG_1 − 0.134 0.397 − 0.118 0.456
Region3 CpG_2 0.548 < 0.001 0.478 0.001
CpG_3 0.565 < 0.001 0.459 0.003
CpG_4 0.200 0.2062 0.235 0.135
  1. P1 and P2 separately indicate the correlation of DNA methylation of CpG site with FADS1 or FADS2 gene expression tested by Pearson’s correlation analysis. FADS fatty acid desaturase