Table 1 Clinical characteristics
546 RP patients included on TMA | ||
Age at RP (years), median (range) | 63 (34–76) | |
Pathological GS | ||
< 7, n (%) | 229 (41.9) | |
≥ 7, n (%) | 317 (58.1) | |
Pathological T stage | ||
≤pT2c, n (%) | 363 (66.5) | |
≥pT3a, n (%) | 182 (33.3) | |
Unknown, n (%) | 1 (0.2) | |
Preoperative PSA | ||
PSA ≤ 10 ng/ml, n (%) | 222 (40.7) | |
PSA > 10 ng/ml, n (%) | 324 (59.3) | |
Surgical margin status | ||
Negative, n (%) | 366 (67.0) | |
Positive, n (%) | 175 (32.1) | |
Unknown, n (%) | 5 (0.9) | |
Follow-up (months), median (range) | 80 (12–158) | |
BCR | ||
No, n (%) | 310 (56.8) | |
Yes, n (%) | 236 (43.2) | |
PC | NM | |
5mC (IHC), n (%) | ||
Total | 344 | 328 |
Score < 1 | – | 3 (0.8) |
Score = 1 | 160 (34.9) | 126 (35.7) |
Score > 1 | 184 (40.2) | 199 (56.4) |
Not determined | 114 (24.9) | 25 (7.1) |
5hmC (IHC), n (%) | ||
Total | 367 | 293 |
Score < 1 | 27 (5.9) | 8 (2.5) |
Score = 1 | 153 (33.4) | 111 (34.0) |
Score > 1 | 187 (40.8) | 174 (53.4) |
Not determined | 91 (19.9) | 33 (10.1) |
5fC (IHC), n (%) | ||
Total | 281 | 259 |
Score < 1 | 155 (33.8) | 163 (50.6) |
Score = 1 | 65 (14.2) | 50 (15.5) |
Score > 1 | 61 (13.3) | 46 (14.3) |
Not determined | 177 (38.6) | 63 (19.6) |
5caC (IHC), n (%) | ||
Total | 351 | 311 |
Score < 1 | 102 (22.2) | 146 (41.4) |
Score = 1 | 96 (21.0) | 60 (17.0) |
Score > 1 | 153 (33.4) | 105 (29.7) |
Not determined | 107 (23.4) | 42 (11.9) |
ERG (IHC), n (%) | ||
Total | 433 | NA |
ERG− | 205 (44.8) | NA |
ERG+ | 228 (49.8) | NA |
Not determined | 25 (5.4) | NA |