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Fig. 9 | Clinical Epigenetics

Fig. 9

From: Dysregulation and prognostic potential of 5-methylcytosine (5mC), 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC) levels in prostate cancer

Fig. 9

Kaplan-Meier analysis: Association between 5caC score and time to BCR after RP. The prognostic value of 5caC score was evaluated through Kaplan-Meier analysis using time to biochemical recurrence after radical prostatectomy as the clinical endpoint. Patients with low 5caC score (≤ 1; blue curves) were compared with patients with high 5caC score (> 1; red curves) in (a) the full PC set, b the ERG− PC subset, and c the ERG+ PC subset. The number of patients in each subgroup is listed at the bottom and p values for 2 -sided log-rank tests are given for each panel. Significant p values are marked by an asterisk (*)

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