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Fig. 4 | Clinical Epigenetics

Fig. 4

From: Dysregulation and prognostic potential of 5-methylcytosine (5mC), 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC) levels in prostate cancer

Fig. 4

Representative images of 5caC immunoreactivity in malignant and non-malignant prostate tissue samples. a TMA core containing both malignant and NM prostate glands, illustrating increased 5caC levels in malignant (IHC score = 2, arrowheads) compared to NM glands (IHC score = 0, arrow). b Strong 5caC staining in a malignant core (IHC score = 2). c Moderate 5caC staining in a malignant core (IHC score = 1). d Weak 5caC staining in a malignant core (IHC score = 0)

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