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Fig. 2 | Clinical Epigenetics

Fig. 2

From: DNA methylation and repressive histones in the promoters of PD-1, CTLA-4, TIM-3, LAG-3, TIGIT, PD-L1, and galectin-9 genes in human colorectal cancer

Fig. 2

Analyses of CpG methylation of immune checkpoint promoters in colorectal tumor and normal tissues. Representative plots show the CpG methylation of the promoter regions together with bar charts of the demethylation percentages of PD-1 (a), CTLA-4 (b), TIM-3 (c), LAG-3 (d), TIGIT (e), PD-L1 (f), and galectin-9 (g) as analyzed by bisulfite sequencing of the genomic DNA isolated from colorectal tumor and normal colon tissues from 14 patients. Methylation status of individual CpG motifs is shown by white (demethylation) or gray (methylation) colors

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Clinical Epigenetics

ISSN: 1868-7083

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