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Fig. 5 | Clinical Epigenetics

Fig. 5

From: Vitamin C increases 5-hydroxymethylcytosine level and inhibits the growth of bladder cancer

Fig. 5

Vitamin C treatment re-establishes the 5hmC landscape in the bladder cancer cell epigenome. a Average 5hmC levels in T24 cells treated with vitamin C or control across different gene-associated regions. b KEGG pathway analysis results for significantly elevated 5hmC peak-associated genes. c KEGG pathway analysis results for overlapping 5hmC peak-associated genes. d GO term analysis results for overlapping 5hmC peak-associated genes. e The hMeDIP-seq results and hMeDIP-qPCR/MeDip-qPCR verifications of representative overlapping LATS2 and RND3 genes. f The enrichment scores of vitamin C-restored 5hmC peaks in different genomic elements. g IPA pathway enrichment analysis for enhancer-assigned genes

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