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Fig. 4 | Clinical Epigenetics

Fig. 4

From: Loss of maternal EED results in postnatal overgrowth

Fig. 4

Offspring from Eeddel/del oocytes have increased bone mineral density and fat content, but reduced lean muscle. ad Postnatal day (PND) 2: bone mineral density (a), lean muscle content (b), fat content (c), ponderal index (d) in WT and HET offspring produced from Eedfl/fl (wt), Eedwt/del (het) and Eeddel/del(hom) oocytes and wild type sperm (ad: WT offspring from wt oocytes n = 28; WT offspring from het oocytes n = 6; HET offspring from het oocytes n = 8; HET offspring from hom oocytes n = 19). *P < 0.05, **P < 0.01, one-way ANOVA plus post hoc Tukey’s multiple comparisons test. Error bars ± SEM

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