Table 4 Integration with gene expression based on correlation statistic
From: Differentially methylated loci in NAFLD cirrhosis are associated with key signaling pathways
Island | Direction | Gene | Correlation | P value | FDR |
|---|---|---|---|---|---|
chr1: 64058937-64059913 | Increased methylation | PGM1 | − 0.69 | 9.31E−03 | 3.30E−02 |
chr1: 6685071-6685691 | Increased methylation | PHF13 | − 0.75 | 2.92E−03 | 1.48E−02 |
chr2: 127817994-127818231 | Increased methylation | BIN1 | − 0.77 | 2.17E−03 | 1.16E−02 |
chr4: 40858884-40859162 | Decreased methylation | APBB2 | − 0.84 | 3.24E−04 | 2.60E−03 |
chr4: 81109887-81110460 | Increased methylation | PRDM8 | − 0.89 | 4.51E−05 | 7.26E−04 |
chr5: 127871958-127872263 | Increased methylation | FBN2 | − 0.88 | 6.81E−05 | 1.01E−03 |
chr6: 13925099-13925510 | Increased methylation | RNF182 | − 0.86 | 1.39E−04 | 1.43E−03 |
chr6: 30038881-30039477 | Increased methylation | RNF39 | − 0.83 | 4.59E−04 | 3.53E−03 |
chr6: 31619856-31620525 | Increased methylation | APOM | − 0.82 | 6.27E−04 | 4.62E−03 |
chr7: 150417414-150418018 | Decreased methylation | GIMAP1 | − 0.92 | 9.67E−06 | 5.82E−04 |
chr7: 1753446-1753706 | Increased methylation | ELFN1 | − 0.64 | 1.73E−02 | 4.94E−02 |
chr7: 27147589-27148389 | Increased methylation | HOXA3 | − 0.90 | 2.79E−05 | 5.82E−04 |
chr7: 27162087-27162426 | Increased methylation | HOXA3 | − 0.89 | 4.37E−05 | 7.26E−04 |
chr7: 27169572-27170638 | Increased methylation | HOXA4 | − 0.86 | 1.45E−04 | 1.43E−03 |
chr8: 134308328-134310145 | Increased methylation | NDRG1 | − 0.73 | 4.57E−03 | 2.07E−02 |
chr8: 145730390-145732205 | Increased methylation | GPT | − 0.88 | 8.23E−05 | 1.12E−03 |
chr8: 27348658-27348883 | Increased methylation | EPHX2 | − 0.79 | 1.20E−03 | 7.05E−03 |
chr8: 59571603-59572526 | Decreased methylation | NSMAF | − 0.79 | 1.35E−03 | 7.72E−03 |
chr9: 99616401-99616940 | Decreased methylation | ZNF782 | − 0.72 | 5.26E−03 | 2.27E−02 |
chr10: 43697777-43698177 | Increased methylation | RASGEF1A | − 0.90 | 2.35E−05 | 5.82E−04 |
chr11: 118781060-118781732 | Decreased methylation | BCL9L | − 0.69 | 8.58E−03 | 3.10E−02 |
chr11: 1330390-1331498 | Increased methylation | TOLLIP | − 0.65 | 1.69E−02 | 4.94E−02 |
chr11: 279072-281700 | Increased methylation | NLRP6 | − 0.71 | 6.03E−03 | 2.48E−02 |
chr11: 70508328-70508617 | Decreased methylation | SHANK2 | − 0.70 | 7.74E−03 | 2.98E−02 |
chr11: 70672834-70673055 | Decreased methylation | SHANK2 | − 0.71 | 6.72E−03 | 2.66E−02 |
chr12: 121163472-121163913 | Increased methylation | ACADS | − 0.91 | 1.25E−05 | 5.82E−04 |
chr15: 60690708-60690930 | Decreased methylation | ANXA2 | − 0.72 | 5.51E−03 | 2.32E−02 |
chr15: 96864881-96866787 | Decreased methylation | NR2F2 | − 0.78 | 1.52E−03 | 8.41E−03 |
chr17: 8649003-8649513 | Increased methylation | CCDC42 | − 0.91 | 1.84E−05 | 5.82E−04 |
chr18: 56530395-56531288 | Decreased methylation | ZNF532 | − 0.66 | 1.49E−02 | 4.70E−02 |
chr19: 6752515-6753657 | Increased methylation | SH2D3A | − 0.80 | 9.31E−04 | 5.88E−03 |
chr20:20433105-20433329 | Decreased methylation | RALGAPA2 | − 0.73 | 4.40E−03 | 2.06E−02 |
chr21: 47648191-47649622 | Increased methylation | LSS | − 0.66 | 1.35E−02 | 4.44E−02 |
chr22: 37420225-37420900 | Increased methylation | MPST | − 0.81 | 8.54E−04 | 5.70E−03 |