Fig. 2
From: Assessment of new HDAC inhibitors for immunotherapy of malignant pleural mesothelioma
Effect of HDAC inhibitors on NK and Treg cells. Lymphocytes obtained by elutriation were treated with HDACi at the following concentrations for 48 h: VPA 5 mM, SAHA 1 μM, ODB 32 μM, NODB 8 μM, ODH 4 μM, and NODH 50 nM. a and c are examples of results obtained on natural killer cells (NK) and regulatory T cells (Treg) using flow cytometry. b and d are graphic representations of HDACi effect on NK and Treg proportions (respectively). Results are expressed as the means ± S.E.M of three independent experiments. *p < 0.05, **p < 0.01 and ***p < 0.001